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Contract and custom fermentation
for flexible production

Find out more

Contract and customised

tailored to your needs

Do you already have a fully established process for your microorganism?
Then we will gladly handle the fermentation for you on a contract basis.
But we can even support you if you do not have a fully established process: We offer strain screening and production adapted to your specific requirements.

If you use us for contract fermentation, we are also happy to develop the media and optimise the process parameters to get the best possible results from your strain.

Flexible production enables

customised order processing and contract fermentations

All benefits at a glance:

  • Aerobic and anaerobic processes

  • Fermentation of prokaryotes and eukaryotes

  • Various process designs

    > batch-to-batch
    > fed-batch

  • Lyophilisate as end product. Harvesting of intermediates for further processing possible

    > Fermentation broth
    > Biomass

  • High quality thanks to continuous production stage monitoring in our own laboratory supported by external analyses

  • Development in our own laboratory

  • Fulfilment of special product requirements (halal, kosher, vegan, allergen-free...)

  • Media sterilisation via heating or filtration possible

Our fermentation plant

for individual customer requests

The MicroTec® plant is designed for production of prokaryotes and eukaryotes. Our fully automated production facilitates a high level of control and reproducibility within the processes. A large amount of parameters (such as temperature, pH value and oxygen concentration) can be precisely controlled throughout the entire process. The system is designed to meet the highest hygiene requirements.

The CIP and SIP facilities optimally fulfil the high hygiene requirements. All cleaning and sterilisation processes run fully automatically, without dismantling machine or system parts.

The process

1

Pre-culture

Starting from a cryopreserved pure strain, pre-cultivation takes place over several stages on a laboratory scale. Pre-cultivation takes place in specially adapted, sterile culture media under optimised conditions.

2

Main culture

The pre-culture prepared through this process is used as an inoculum. Production on an industrial scale takes place in a bioreactor under strain-specific controlled process parameters.

3

Separation

At the point of highest cell yield or cell activity, the microorganisms are separated from the medium through centrifugation.

4

Drying

Due to the demanding conditions during freeze-drying, the harvested biomass is treated with protective substances.

The subsequent gentle freeze-drying process takes place in one of our modern facilities. If required, we can also utilise the spray drying process.

The biomass and the finished lyophilisate are processed in a highly hygienic area.

5

Filling and standardisation

Depending on the required activity in the application, the pure strain is standardised with various carrier substrates and filled based on specifically defined parameters.

Industries in which microorganisms produced by us

already solve special challenges.

MicroTec® develops and produces microorganisms for the food and beverage industry, agriculture and healthcare. The application areas here are just as diverse as the industries themselves.